Monthly Archives: March 2019

laboratory notebooks

Global Pharmaceutical Outlook: 3 Biggest Pharma Companies In the World

The global pharmaceutical market is projected to reach $1.12 trillion by 2022. Across the U.S. and the world, there are millions of students, researchers, assistants, and pharmacists working toward bettering the industry and helping those in need of medical help.

The pharma industry discovers, develops, produces, and markets pharmaceutical drugs for use as medications to be administered to patients to vaccinate them, alleviate a symptom, or cure them of diseases.

College campuses are filled with kids lugging their laboratory notebooks and equipment to learn the ins and outs of the industry. And those already working in the pharmaceutical field are doing everything they can to develop new medications that could potentially change the world for the better.

Pharma companies deal in either generic or brand medications and medical devices (or both) and are subject to a variety of laws and regulations that govern the patenting, testing, safety, and marketing of each product.

Here are some of the biggest pharmaceutical companies across the globe:

  • Pfizer — Pfizer remains the largest pharma organization in the world, worth around $52.5 billion. This research-based company deals with immunology, oncology, neurosciences, and rare diseases.
  • Roche — Worth approximately $44.3 billion, this Swiss pharma company employs 93,734 people across the globe. Roche develops innovative drugs and devices to fight infectious diseases and other health issues.
  • Sanofi — Sanofi is a French company worth $36.6 billion. They saw a 4.2% revenue growth for its pharmaceutical products, contributing to 85% of the company’s total revenue. A quarter of all their pharma revenue came from their three best selling medications: Lantus, an insulin injection for diabetes, Aubagio, a once-daily pill to treat a form of multiple sclerosis, and Lovenox, an anticoagulant to prevent blood clots.

If you are involved in this thriving industry or are a student and want to keep track of all your notes, ideas, formulas, and more; you’re going to need some quality laboratory notebooks. Both students and professionals alike can benefit from lab notebooks and will likely use the same ones (and more) for decades.

Contact Scientific Notebook Company right away for some quality laboratory notebooks!

laboratory notebooks

The Drug Development Process: 3 Essential Steps

Medications and vaccinations are essential to everyday life. Over the years, there have been tens of thousands of medications that have been developed in order to help with everything from chronic pain management to life-threatening diseases.

Typically, it takes anywhere from 10 to 15 years to develop a medicine or vaccine. Researchers, scientists, and healthcare professionals are constantly updating their laboratory notebooks and making strides toward revolutionary breakthroughs within the scientific and medical sector.

How does a drug, medication, or vaccination go from the pages of laboratory notebooks to pharmacies, doctor’s offices, and medicine cabinets around the world?

The Drug Development Process

The success rate of experimental medications making it to pharmacy shelves and medicine cabinets is actually quite low. Currently, there are more than 180,000 ongoing clinical studies across the U.S. and world. That being said, since the Food and Drug Administration (FDA) came into existence in 1938, only 1,453 drugs have been approved through the end of 2013. Similarly, according to, only five out of every 5,000 preclinical drugs will ever be tested on humans.

Here are a few essential steps that need to be taken during the drug development process:

  • Discovery and target validation — First, discovery work needs to be done. This is where drug development organizations select a molecule, such as a gene or protein, to target with a drug. This is also where pages and pages of scientific notebooks are filled with thoughts, notes, ideas, and more.
  • Preclinical testing — Next, in vitro and in vivo testing begins. In vitro testing takes a look at how the drug’s molecules interact inside test tubes. In vivo testing involves testing those molecules on living cell cultures (not humans).
  • Clinical studies — The third step actually involves three separate phases of clinical studies. Phase 1 involves a relatively small group of healthy people and focuses entirely on safety; phase 2 involves 100 or more patients who are no longer healthy volunteers; and phase 3 studies are designed by drug developers and approved by the FDA with guidelines for clearly defined primary endpoints to determine the success or failure of a drug being tested on a specific health condition.

If you want to learn more about the medication or vaccination process, or find high-quality laboratory notebooks to keep track of all the information you obtain along your scientific journey, contact Scientific Notebook Company right away!